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    What an IVF cycle actually looks like, week by week

    Reviewed by HHH Clinical Team · April 2026

    1 section · 1 min read

    Fertility & Treatment
    1 minHHH clinical team
    WHAT ARE THE SIX STAGES OF AN IVF CYCLE?

    What are the six stages of an IVF cycle?

    When people say 'I am doing ', they usually mean a sequence of six distinct phases over six to eight weeks. Most clinics break it down differently in their leaflets. We are using the patient experience as the spine, not the clinic workflow.

    1. 1. Down-regulation or natural start

      Some protocols start with two to three weeks of medication that quietens your own cycle so the clinic can control timing. Other protocols (antagonist or natural-cycle IVF) skip this. You will know which protocol applies because it changes which days you start injections.

    2. 2. Stimulation, around 10 to 14 days

      Daily injections of follicle-stimulating hormone (FSH) push your ovaries to grow several follicles instead of one. Scans every two to four days track the size and number. This is the part that most people find physically demanding: bloating, mood swings, and the discipline of daily injections at the same time each day.

    3. 3. Trigger and egg collection

      When the follicles are the right size, a final 'trigger' injection ripens the eggs. Egg collection happens about 36 hours later under light sedation. It takes 15 to 30 minutes. Most people go home within a few hours and feel sore for a day or two.

    4. 4. Fertilisation in the lab

      Eggs are mixed with sperm (conventional IVF) or each egg is injected with a single sperm (ICSI). Embryos are watched in the lab for three to five days. Not every egg fertilises, not every embryo divides well. The clinic will update you each day with numbers, which can be emotionally hard.

    5. 5. Transfer or freeze-all

      A single embryo is usually placed in the uterus on day 3 or day 5 (blastocyst). Some clinics freeze all embryos and transfer in a later cycle to give the lining time to recover from stimulation. Frozen-embryo-transfer cycles are increasingly common.

    6. 6. Two-week wait, then test

      About 9 to 14 days after transfer, a blood test (or home pregnancy test, depending on clinic) confirms whether the cycle worked. Many people describe this as the hardest part. If positive, an early scan follows in two to three weeks. If not, the clinic talks through what was learnt and what comes next.

    The grey zone

    Fresh embryo transfer vs freeze-all-then-transfer

    Standard position · Global

    Both approaches achieve broadly similar live birth rates in unselected populations. UK NICE and most international bodies treat them as alternatives.

    Where it gets more nuanced

    What we honestly do not know

    Long-term child outcomes from frozen-cycle pregnancies are still being studied as the freeze-all approach is more recent. Current data is reassuring but the cohort is younger than the fresh-cycle cohort.

    Bottom line

    If your clinic recommends one approach over the other, ask which patient group their recommendation is based on. The right answer is patient-specific, not clinic-default.

    References

    1. [1] 30407510Roque M et al. Fresh versus elective frozen embryo transfer in IVF cycles: a systematic review and meta-analysis. Hum Reprod Update 2019;25(1):2-14.

    Browse the full evidence library →

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    References

    1. [1] nice-cg156-fertility-2026NICE Clinical Guideline CG156: Fertility problems: assessment and treatment.
    2. [2] hfea-uk-fertility-treatment-2024Human Fertilisation and Embryology Authority (HFEA): Fertility treatment 2024, preliminary trends and figures.
    3. [3] 30407510Roque M et al. Fresh versus elective frozen embryo transfer in IVF cycles: a systematic review and meta-analysis. Hum Reprod Update 2019;25(1):2-14.

    Browse the full evidence library →

    Reviewed by clinicians

    Authored and reviewed by clinicians from the founding team. Information only, not personalised medical advice.